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NP-G2-044
CAS No. 1807454-59-6
NP-G2-044( —— )
Catalog No. M23818 CAS No. 1807454-59-6
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 112 | In Stock |
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| 2MG | 65 | In Stock |
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| 5MG | 96 | In Stock |
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| 10MG | 143 | In Stock |
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| 25MG | 296 | In Stock |
|
| 50MG | 440 | In Stock |
|
| 100MG | 644 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1358 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNP-G2-044
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NoteResearch use only, not for human use.
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Brief DescriptionNP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
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DescriptionNP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
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In Vitro——
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In VivoAnimal Model:6-8 week old female BALB/c mice (mouse model bearing 4T1 tumor cells) Dosage:100 mg/kg Administration:I.p.; daily for 18 days Result:Inhibition of 4T1 mouse mammary tumor cell metastasis to the lung.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorfascin
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Research Area——
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Indication——
Chemical Information
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CAS Number1807454-59-6
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Formula Weight399.37
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Molecular FormulaC21H16F3N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (250.39 mM; Need ultrasonic)
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SMILESCc(occ1)c1C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2c1cccc2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10(7):966-980.
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