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ML303
CAS No. 1638211-04-7
ML303( —— )
Catalog No. M23735 CAS No. 1638211-04-7
ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 104 | In Stock |
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| 5MG | 93 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 258 | In Stock |
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| 50MG | 368 | In Stock |
|
| 100MG | 548 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML303
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NoteResearch use only, not for human use.
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Brief DescriptionML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
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DescriptionML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
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In VitroML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells. Western Blot Analysis Cell Line:MDCK cells infected with A/PR/8/34, at a MOI of 2, for 6 hours.Concentration:20 μM.Incubation Time:6 hours. Result:Restored IFN-β mRNA levels in MDCK cells.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetInfluenza Virus
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RecptorH1N1
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Research Area——
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Indication——
Chemical Information
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CAS Number1638211-04-7
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Formula Weight399.37
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Molecular FormulaC21H16F3N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESOC1=CC=C(C2=CC=NC3=C2C(C)=NN3C4=CC=C(C(F)(F)F)C=C4)C=C1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Eleutheroside B1
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.
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M2WJ-332
A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM.
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CBS1117
CBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1).?It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
