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Etripamil

CAS No. 1593673-23-4

Etripamil( MSP-2017 | (-)-MSP-2017 )

Catalog No. M23694 CAS No. 1593673-23-4

Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 173 In Stock
25MG 312 In Stock
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Biological Information

  • Product Name
    Etripamil
  • Note
    Research use only, not for human use.
  • Brief Description
    Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel.
  • Description
    Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel. It has a rapid onset of action designed for intranasal administration. It is also used to treat Paroxysmal Supraventricular Tachycardia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MSP-2017 | (-)-MSP-2017
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    L-type calcium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1593673-23-4
  • Formula Weight
    452.59
  • Molecular Formula
    C27H36N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol : 110 mg/mL (243.05 mM; Need ultrasonic)
  • SMILES
    O=C(OC)C1=CC=CC(CCN(CCC[C@](C2=CC=C(OC)C(OC)=C2)(C#N)C(C)C)C)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497.
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