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Home - Products - Chromatin/Epigenetic - COX - Licofelone

Licofelone

CAS No. 156897-06-2

Licofelone( ML-3000 )

Catalog No. M23680 CAS No. 156897-06-2

Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 39 In Stock
5MG 47 In Stock
10MG 87 In Stock
25MG 147 In Stock
50MG 219 In Stock
100MG 323 In Stock
200MG 480 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Licofelone
  • Note
    Research use only, not for human use.
  • Brief Description
    Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory.
  • Description
    Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ML-3000
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    5-LOX|COX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    156897-06-2
  • Formula Weight
    379.88
  • Molecular Formula
    C23H22ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (65.81 mM; Need ultrasonic)
  • SMILES
    CC(C)(C1)Cn(c(CC(O)=O)c2-c(cc3)ccc3Cl)c1c2-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tavolari S, et al. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. Carcinogenesis. 2008 Feb;29(2):371-80.
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