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AF38469
CAS No. 1531634-31-7
AF38469( AF-38469 )
Catalog No. M23661 CAS No. 1531634-31-7
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
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| 2MG | 117 | In Stock |
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| 5MG | 180 | In Stock |
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| 10MG | 282 | In Stock |
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| 25MG | 550 | In Stock |
|
| 50MG | 830 | In Stock |
|
| 100MG | 1135 | In Stock |
|
| 200MG | 1516 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAF38469
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NoteResearch use only, not for human use.
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Brief DescriptionAF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
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DescriptionAF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
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In Vitro——
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In Vivo——
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SynonymsAF-38469
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PathwayGPCR/G Protein
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TargetNeurotensin Receptor
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RecptorSortilin
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Research Area——
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Indication——
Chemical Information
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CAS Number1531634-31-7
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Formula Weight324.25
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Molecular FormulaC15H11F3N2O3
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Purity>98% (HPLC)
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SolubilityDMSO:40 mg/mL (123.36 mM)
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SMILESCc1cccc(NC(c(ccc(C(F)(F)F)c2)c2C(O)=O)=O)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schroder TJ, et al. The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.
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