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Lotilaner
CAS No. 1369852-71-0
Lotilaner( —— )
Catalog No. M23521 CAS No. 1369852-71-0
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 107 | In Stock |
|
| 2MG | 50 | In Stock |
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| 5MG | 82 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 335 | In Stock |
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| 50MG | 538 | In Stock |
|
| 100MG | 863 | In Stock |
|
| 200MG | 1163 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLotilaner
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NoteResearch use only, not for human use.
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Brief DescriptionLotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors.
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DescriptionLotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetOther Targets
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RecptorGABA|Parasite
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Research Area——
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Indication——
Chemical Information
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CAS Number1369852-71-0
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Formula Weight596.76
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Molecular FormulaC20H14Cl3F6N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO: 150 mg/mL (251.36 mM)
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SMILESCc1c(C(NCC(NCC(F)(F)F)=O)=O)sc(C(C2)=NO[C@]2(C(F)(F)F)c(cc2Cl)cc(Cl)c2Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lotilaner, et al. The novel isoxazoline ectoparasiticide lotilaner (Credelio?): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors. 2017 Nov 1;10(1):530.
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