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CID44216842
CAS No. 1222513-26-9
CID44216842( KUC103479N-02 )
Catalog No. M23391 CAS No. 1222513-26-9
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 46 | In Stock |
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| 10MG | 78 | In Stock |
|
| 25MG | 162 | In Stock |
|
| 50MG | 252 | In Stock |
|
| 100MG | 370 | In Stock |
|
| 200MG | 528 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCID44216842
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NoteResearch use only, not for human use.
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Brief DescriptionCID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.
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DescriptionCID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
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In VitroCID44216842 inhibits GTP binding to both Cdc42 and its mutant in a dose-dependent manner. The inhibition is specific toward Cdc42 with no effects on other GTPases including Rac and Rho in the same family.
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In Vivo——
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SynonymsKUC103479N-02
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PathwayAngiogenesis
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TargetCDK
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RecptorCdc42
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Research Area——
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Indication——
Chemical Information
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CAS Number1222513-26-9
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Formula Weight486.38
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Molecular FormulaC22H20BrN3O3S
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL?(514.00 mM;?Need ultrasonic)
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SMILESO=S(C1=CC=C(N2N=C(C3=CC=CC(OC)=C3)CC2C4=CC=C(Br)C=C4)C=C1)(N)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.
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