Cart
sales@molnova.com
ROCK inhibitor-2
CAS No. 1127308-52-4
ROCK inhibitor-2( —— )
Catalog No. M23320 CAS No. 1127308-52-4
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 97 | In Stock |
|
| 5MG | 160 | In Stock |
|
| 10MG | 259 | In Stock |
|
| 25MG | 520 | In Stock |
|
| 50MG | 750 | In Stock |
|
| 100MG | 1035 | In Stock |
|
| 500MG | 2061 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameROCK inhibitor-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
-
DescriptionROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetROCK
-
RecptorROCK1|ROCK2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1127308-52-4
-
Formula Weight332.4
-
Molecular FormulaC21H20N2O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:250 mg/mL (752.11 mM; Need ultrasonic)
-
SMILESO=C(N[C@@H](C1=CC=CC(OC)=C1)C)C2=CC=C(C3=CC=NC=C3)C=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.
molnova catalog
related products
-
Chroman 1
Chroman 1 is a potent inhibitor of ROCK1 (IC50?= 52 pM) and ROCK2 (IC50?= 1 pM).
-
CAY10746
CAY10746 is a selective Rho kinase (ROCK) inhibitor, targeting ROCK I and ROCK II with IC50 values of 0.014 μM and 0.003 μM, respectively.
-
Cotosudil
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity and is used to treat or prevent diseases or conditions caused by cataracts, cardiovascular or neurodegenerative diseases or nerve damage.
