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CBS1117
CAS No. 959245-08-0
CBS1117( —— )
Catalog No. M22993 CAS No. 959245-08-0
CBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 71 | In Stock |
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| 2MG | 35 | In Stock |
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| 5MG | 56 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 169 | In Stock |
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| 50MG | 249 | In Stock |
|
| 100MG | 369 | In Stock |
|
| 200MG | 517 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCBS1117
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NoteResearch use only, not for human use.
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Brief DescriptionCBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
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DescriptionCBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1). It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
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In VitroCBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549).
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetInfluenza Virus
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Recptorinfluenza A virus
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Research Area——
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Indication——
Chemical Information
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CAS Number959245-08-0
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Formula Weight315.24
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Molecular FormulaC15H20Cl2N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (793.05 mM)
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SMILESO=C(NC1CCN(C(C)C)CC1)C2=C(Cl)C=CC=C2Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hussein AFA, et al. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782.
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