Terbutaline

Research use only, not for human use.

Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.

Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.

Terbutaline (0-10 μM, 1 hour) enhances MKP-1 expression in activated mouse macrophages.RT-PCR Cell Line:J774 macrophages Concentration:0-10 μM Incubation Time:1 hour Result:Enhanced MKP-1 expression in J774 macrophages in a dose-dependent manner.Western Blot Analysis Cell Line:J774 macrophages Concentration:100 nM Incubation Time:1 hour Result:Reduced the phosphorylation of p38 MAPK in J774 macrophages.

Terbutaline (intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days) treatment can improve the allodynia in ob/ob mice. Animal Model:Adult male ob/ob miceDosage:0.5 mg/kg Administration:Intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days Result:Reversed the mechanical allodynia in ob/ob mice.

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Angiogenesis

Adrenergic Receptor

β2-adrenergic receptor

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23031-25-6

225.3

C12H19NO3

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (1109.73 mM)

OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1

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(-20℃)

With Ice Pack

≥ 2 years