Phenylacetylglutamine is a normal constituent of human urine but other mammals such as the dog cat rat monkey sheep and horse do not excrete this compound. Phenylacetylglutamine is a major nitrogenous metabolite that accumulates in uremia. Phenylacetylglutamine also is a microbial metabolite found in Christensenellaceae Lachnospiraceae and Ruminococcaceae.

4'-Methoxyisoagarotetrol is chromone derivative and shows moderate PDE?3A inhibitory activity (IC50=54 μM).

AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.