Cart
sales@molnova.com
Urolithin B
CAS No. 1139-83-9
Urolithin B( —— )
Catalog No. M22685 CAS No. 1139-83-9
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 83 | In Stock |
|
| 1G | 142 | In Stock |
|
Biological Information
-
Product NameUrolithin B
-
NoteResearch use only, not for human use.
-
Brief DescriptionUrolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
-
DescriptionUrolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB| JNK| ERK| Akt| AMPK| Human Endogenous Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1139-83-9
-
Formula Weight212.2
-
Molecular FormulaC13H8O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:249 mg/mL(1173.42 mM)
-
SMILESOc1ccc2c(c1)oc(=O)c1ccccc21
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57.
molnova catalog
related products
-
Cynaropicrin
Cynaropicrin, a sesquiterpene lactone found in artichoke (Cynara scolymus), has anti-hepatitis C and trypanosome activity and inhibits NF-κB activation.
-
NF-κΒ activator 1
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
-
GGTI 2147
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
