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Urolithin B
CAS No. 1139-83-9
Urolithin B( —— )
Catalog No. M22685 CAS No. 1139-83-9
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 83 | In Stock |
|
| 1G | 142 | In Stock |
|
Biological Information
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Product NameUrolithin B
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NoteResearch use only, not for human use.
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Brief DescriptionUrolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
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DescriptionUrolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB| JNK| ERK| Akt| AMPK| Human Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number1139-83-9
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Formula Weight212.2
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Molecular FormulaC13H8O3
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Purity>98% (HPLC)
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SolubilityDMSO:249 mg/mL(1173.42 mM)
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SMILESOc1ccc2c(c1)oc(=O)c1ccccc21
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Scandoside
Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
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Magnolol
Magnolol is isomeric to honokiol (sc-202653). Magnolol is an anxiolytic,anti-thrombotic and antibacterial.
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Aurantiamide
Aurantiamide has anti-cancer anti-inflammatory and antinociceptive activities it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB JNK and p38 pathways.
