Niclosamide-olamine

Research use only, not for human use.

Niclosamide-olamine is an Repellent, Insect Attractant and Chemosterilant.

Niclosamide-olamine is an Repellent, Insect Attractant and Chemosterilant.

Cell Viability Assay Cell Line:BD140A, SW-13 and NCI-H295R cells Concentration:0.6 nM-46 μM Incubation Time:Result:Inhibited cellular proliferation in adrenocortical carcinoma cell lines with the IC50 of 0.12 μM, 0.15 μM, and 0.53 μM in BD140A, SW-13, and NCI-H295R, respectively. Cell Viability Assay Cell Line:Hela cells Concentration:0.05-5 μM Incubation Time:24 hours Result:Inhibited STAT3-mediated luciferase reporter activity with an IC50 of 0.25 μM.Cell Viability Assay Cell Line:Vero E6 cells Concentration:10 μM Incubation Time:2 days Result:Inhibited the synthesis of viral antigens of SARS-CoV in Vero E6 cells.

Animal Model:Nu+/Nu+ mice injected with NCI-H295R cells Dosage:100 mg/kg, 200 mg/kg Administration:Oral gavage; 100 mg/kg, 200 mg/kg; once a week; 8 weeks Result:Showed a 60%-80% inhibition in tumor growth, as compared to the control group.

Niclosamide Ethanolamine salt

Others

Other Targets

Others

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1420-04-8

388.2

C15H15Cl2N3O5

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (322.00 mM)

NCCO.Oc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O

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(-20℃)

With Ice Pack

≥ 2 years