Cart
sales@molnova.com
GRP-60367
CAS No. 1309241-34-6
GRP-60367( —— )
Catalog No. M22631 CAS No. 1309241-34-6
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 183 | In Stock |
|
| 5MG | 169 | In Stock |
|
| 10MG | 258 | In Stock |
|
| 25MG | 426 | In Stock |
|
| 50MG | 586 | In Stock |
|
| 100MG | 792 | In Stock |
|
| 200MG | 1051 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGRP-60367
-
NoteResearch use only, not for human use.
-
Brief DescriptionGRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
-
DescriptionGRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
-
In VitroGRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52?nM on different host cell lines.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorRABV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1309241-34-6
-
Formula Weight353.46
-
Molecular FormulaC21H27N3O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCc1ccc(C)c(OCCNC2CCN(CC2)C(=O)c2ccncc2)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Pont V D , Wirblich C , Yoon J J , et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor[J]. Journal of Virology, 2020, 94(13).
molnova catalog
related products
-
LCMV gp33-41 (TFA) (...
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes.
-
Sanggenone H
Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α2 and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.
-
(Z)-9-nonadecene
(Z)-9-Nonadecene was identified the first time in T. melanocephalum. (Z)-9-Nonadecene is a major component in mandibular glands and iridodials are produced in pygidial glands.
