Cart
sales@molnova.com
Venlafaxine
CAS No. 93413-69-5
Venlafaxine( Wy 45030 )
Catalog No. M22585 CAS No. 93413-69-5
Venlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 36 | In Stock |
|
| 5MG | 30 | In Stock |
|
| 10MG | 49 | In Stock |
|
| 25MG | 69 | In Stock |
|
| 50MG | 99 | In Stock |
|
| 100MG | 146 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 365 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVenlafaxine
-
NoteResearch use only, not for human use.
-
Brief DescriptionVenlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
-
DescriptionVenlafaxine, an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
-
In VitroVenlafaxine (Wy 45030) dose-dependently inhibits binding of the serotonin transporter radioligand [3H]-paroxetine to membranes from cells transfected with the human 5-HT transporter with a Ki of 2.48 μM. Venlafaxine inhibits binding of the NE transporter ligand [3H]-nisoxetine to membranes from cells transfected with the human NE transporter with a Ki of 82 nM.Venlafaxine inhibits ex vivo binding to rat 5-HT transporters and NE transporters with ED50 values of 2 and 54 mg/kg, respectively.
-
In VivoVenlafaxine (Wy 45030; 10-100 mg/kg; IP) dose-dependently blocks the depletion of norepinephrine levels in rat hypothalamus induced by 6-OHDA. Animal Model:Male Sprague-Dawley rats weighing 180-230 gramsDosage:10, 30, 100 mg/kg Administration:IP; one hour prior to p-chloramphetamine hydrochloride (p-CA; 10 mg/kg; i.p.)Result:Dose-dependently blocked the depletion of norepinephrine levels in rat hypothalamus induced by 6-OHDA (intracerebroventricularly; 50 μg/rat; one hour later), with ED50 values of 12 and 94 mg/kg, respectively.
-
SynonymsWy 45030
-
PathwayOthers
-
TargetOther Targets
-
Recptorserotonin-norepinephrine reuptake
-
Research Areanervous system
-
IndicationPanic Disorder
Chemical Information
-
CAS Number93413-69-5
-
Formula Weight277.4
-
Molecular FormulaC17H27NO2
-
Purity>98% (HPLC)
-
SolubilityDMSO:52 mg/mL (187.45mM)
-
SMILESCOc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Cyclo(Tyr-Pro)
Cyclo(Tyr-Pro) shows antibacterial activity towards several marine bacterial species, it also shows weak antagonistic activity against VEGFR2 -CD. Cyclo(Tyr-Pro) and cyclo(Pro-Val) are toxic to both suspension cells and seedlings of Pinus thunbergii, which may offer some clues to research the mechanism of pine wilt disease caused by pine wood nematode.
-
Protogracillin
Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW) which may inhibit platelet aggregation (PAG) and thrombosis. Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action.
-
3-Methyl-2-buten-1-o...
Prenol is found in blackcurrant. Prenol is a constituent of ylang-ylang and hop oils. Prenol is found in orange peel oil and various fruits e.g. orange lemon lime grape pineapple purple passion fruit loganberry etc. Prenol is a flavouring ingredient
