Cart
sales@molnova.com
Pinacidil monohydrate
CAS No. 85371-64-8
Pinacidil monohydrate( —— )
Catalog No. M22560 CAS No. 85371-64-8
Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 10MG | 28 | In Stock |
|
| 25MG | 46 | In Stock |
|
| 50MG | 72 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePinacidil monohydrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionPinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.
-
DescriptionPinacidil monohydrate is a potassium channel activator, antihypertensive drug.Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki of 104 and 251 nM, respectively.(In Vitro):Pinacidil monohydrate is a potassium channel activator. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers". Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively.
-
In VitroPinacidil monohydrate is a potassium channel activator. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers". Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively.
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorPotassium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number85371-64-8
-
Formula Weight263.34
-
Molecular FormulaC13H21N5O
-
Purity>98% (HPLC)
-
SolubilityDMSO:97 mg/mL (368.35mM; Need ultrasonic); Ethanol:47 mg/mL (178.48mM; Need ultrasonic)
-
SMILESO.CC(N\C(NC#N)=N\c1ccncc1)C(C)(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gollasch M, et al. Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J Pharmacol Exp Ther. 1995 Nov;275(2):681-92.
molnova catalog
related products
-
Hexachlorophene
Hexachlorophene(Hexachlorofen) is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM; also is an inhibitor of Wnt/beta-catenin signaling.
-
OR-1896
OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.
-
Mitiglinide calcium
An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells.
