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SP-146
CAS No. ——
SP-146( —— )
Catalog No. M22413 CAS No. ——
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 357 | In Stock |
|
| 10MG | 597 | In Stock |
|
| 25MG | 882 | In Stock |
|
| 50MG | 1350 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSP-146
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NoteResearch use only, not for human use.
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Brief DescriptionSP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
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DescriptionSP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetAurora Kinase
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RecptorAurora B
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight453.47
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Molecular FormulaC25H20FN7O
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Purity>98% (HPLC)
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SolubilityDMSO:91 mg/mL (200.67 mM)
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SMILESCn1cc(cn1)c2ccc5c(c2)ncnc5Nc4cccc(NC(=O)Nc3cccc(F)c3)c4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lakkaniga R , Zhang L , Belachew B , et al. Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression[J]. European Journal of Medicinal Chemistry, 2020, 203:112589.
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