AA92593

CAS No. 457961-34-1

AA92593( —— )

Catalog No. M22213 CAS No. 457961-34-1

AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 49 In Stock
5MG 45 In Stock
10MG 76 In Stock
25MG 155 In Stock
50MG 268 In Stock
100MG 456 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AA92593
  • Note
    Research use only, not for human use.
  • Brief Description
    AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation.
  • Description
    AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation. Under this situation neither AANAT nor melatonin levels changed under light conditions . The discovery of melanopsin in the lens opens the possibility of regulating melatonin synthesis with the corresponding implication as an antioxidant substance.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    melanopsin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    457961-34-1
  • Formula Weight
    269.36
  • Molecular Formula
    C13H19NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc(cc1C)[S](=O)(=O)N2CCCCC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Alkozi H A , Wang X , Jesus P D L M , et al. Presence of melanopsin in human crystalline lens epithelial cells and its role in melatonin synthesis[J]. Experimental Eye Research, 2016:168.
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