2,4,6-Triiodophenol

Research use only, not for human use.

2,4,6-Triiodophenol is used as an iodinated disinfection by product formed during chlorination of sewage effluents.

2,4,6-Triiodophenol is used as an iodinated disinfection by product formed during chlorination of sewage effluents. It is also used as a potent thyroid disrupting chemical and to investigate deiodinase.

2,4,6-Triiodophenol (5-50 μM; 0-100 h) impairs the quality of pre-implantation mouse embryos in a dose-dependent manner, inducing decline of both total and trophectoderm cell numbers.2,4,6-Triiodophenol (5?μM; 85 h) shows increasement of apoptotic cells in mouse pre-implantation embryos.2,4,6-Triiodophenol (5-50?μM; 100 h) induces oxidative stress in mouse pre-implantation embryos. Apoptosis AnalysisCell Line:Mouse blastocyst cells Concentration:5?μM Incubation Time:85?hours Result:Showed signals of activated Caspase-3/7.Immunofluorescence Cell Line:Mouse blastocyst cells Concentration:5-50?μM Incubation Time:100?hours Result:Resulted in marked increase of oxygen species (ROS) treated with high dose of 2,4,6-Triiodophenol.

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Others

Other Targets

Transthyretin (human)

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609-23-4

471.8

C6H3I3O

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (529.89 mM)

Oc1c([I])cc([I])cc1[I]

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(-20℃)

With Ice Pack

≥ 2 years