ML318( —— )

Catalog No. M22095 CAS No. 1610516-67-0

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	34	In Stock
5MG	30	In Stock
10MG	51	In Stock
25MG	107	In Stock
50MG	170	In Stock
100MG	269	In Stock
200MG	383	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ML318
Note

Research use only, not for human use.
Brief Description

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
Description

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PvdQ acylase
Research Area

——
Indication

——

Chemical Information

CAS Number

1610516-67-0
Formula Weight

280.22
Molecular Formula

C14H8F4N2?
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (356.86 mM)
SMILES

Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.

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