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ML318
CAS No. 1610516-67-0
ML318( —— )
Catalog No. M22095 CAS No. 1610516-67-0
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 34 | In Stock |
|
| 5MG | 30 | In Stock |
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| 10MG | 51 | In Stock |
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| 25MG | 107 | In Stock |
|
| 50MG | 170 | In Stock |
|
| 100MG | 269 | In Stock |
|
| 200MG | 383 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML318
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NoteResearch use only, not for human use.
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Brief DescriptionML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
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DescriptionML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPvdQ acylase
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Research Area——
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Indication——
Chemical Information
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CAS Number1610516-67-0
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Formula Weight280.22
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Molecular FormulaC14H8F4N2?
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (356.86 mM)
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SMILESFc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.
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