Tyrphostin AG 112

CAS No. 144978-82-5

Tyrphostin AG 112( —— )

Catalog No. M22092 CAS No. 144978-82-5

Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 61 In Stock
25MG 122 In Stock
50MG 179 In Stock
100MG 267 In Stock
200MG Get Quote In Stock
500MG 647 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tyrphostin AG 112
  • Note
    Research use only, not for human use.
  • Brief Description
    Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.
  • Description
    Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    144978-82-5
  • Formula Weight
    236.23
  • Molecular Formula
    C13H8N4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (529.15 mM)
  • SMILES
    NC(=C(/C#N)C#N)\C(C#N)=C\c1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447(6):830-9.
molnova catalog
related products
  • AG-1517

    PD153035 hydrochloride is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.

  • Labuxtinib

    Labutinib is a selective inhibitor of the c-kit tyrosine kinase .

  • AG-825

    AG-825(Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.