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Alprenolol hydrochloride
CAS No. 13707-88-5
Alprenolol hydrochloride( —— )
Catalog No. M22090 CAS No. 13707-88-5
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 50MG | 33 | In Stock |
|
| 100MG | 55 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 196 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAlprenolol hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAlprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
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DescriptionAlprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
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In Vitro——
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In VivoAlprenolol (p.o., 50 mg/kg) hydrochloride causes a significant drop in blood pressure which averages 20 mm Hg (at 3-hr) and an increase in heart rate by 39 beats/min (at 3-hr) in conscious renal hypertensive dogs.Alprenolol (i.p., 5 mg/kg) hydrochloride effectively blockes the anxiolytic effects of indorenate and ipsapirone but do not reduce the motor activity in adult male Swiss Webster mice.Alprenolol (intravenous injection, 0.5 or 1.0 mg/kg) can decrease systolic pressure by a mean of 10 mm Hg, diastolic pressure by a mean of 10 mm Hg) hydrochloride and heart rate by 23 beats/min, as well as slightly reduce both myocardial and liver blood flows by mean of 17% and 15% respectively at a dose of 1.0 mg/kg in cats.
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT1A
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Research Area——
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Indication——
Chemical Information
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CAS Number13707-88-5
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Formula Weight285.81
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Molecular FormulaC15H24ClNO2
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Purity>98% (HPLC)
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SolubilityDMSO:95 mg/mL (332.39 mM; Need ultrasonic); H2O:50 mg/mL (174.94 mM; Need ultrasonic)
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SMILESCl.CC(C)NCC(O)COc1ccccc1CC=C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Millan MJ et al. Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther, 1994 Jan, 268(1):337-52.
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