Galnon( —— )

Catalog No. M22086 CAS No. 475115-35-6

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HNMR

HPLC

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Product Name

Galnon
Note

Research use only, not for human use.
Brief Description

Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue propertiesGalnon has been characterized to inhibit seizures, decrease feeding behaviour, diminish physical signs of opiate withdrawal and to alleviate heat-hyperalgesic response to partial sciatic nerve injury.
Description

Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue propertiesGalnon has been characterized to inhibit seizures, decrease feeding behaviour, diminish physical signs of opiate withdrawal and to alleviate heat-hyperalgesic response to partial sciatic nerve injury[1]. Galnon, a GAL receptor agonist, may enhance osteoclastic bone resorption in OVX rats. Although galnon reduced bone volume, biomechanical testing revealed that bone of galnon-treated animals was mechanically superior per unit area. Taken together, galnon simultaneously improves the intrinsic quality of cortical bone whilst stimulating osteoclastic activity in the OVX rat model.
In Vitro

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In Vivo

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Synonyms

——
Pathway

GPCR/G Protein
Target

Neuropeptide Y Receptor
Recptor

Galanin receptor
Research Area

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Indication

——

CAS Number

475115-35-6
Formula Weight

678.83
Molecular Formula

C40H46N4O6
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc34)ccc12
Chemical Name

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1. Sollenberg U , Bartfai T , Langel U . Galnon - A low-molecular weight ligand of the galanin receptors[J]. Neuropeptides, 2005, 39(3):161-163.

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