Centhaquine

Research use only, not for human use.

Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.

Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.(In Vivo):Centhaquine (Centhaquin) (intravenous injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner.Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci.Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of catecholamines, improving both the macro- and microcirculation during CPR.

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Centhaquine,PMZ-2010

Others

Other Targets

Others

Others

Hypovolemic Shock

57961-90-7

331.45

C22H25N3

>98% (HPLC)

DMSO:60 mg/mL (181.02 mM; Need ultrasonic)

CC1=CC(=CC=C1)N1CCN(CCC2=NC3=CC=CC=C3C=C2)CC1

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(-20℃)

With Ice Pack

≥ 2 years