BAY-545

CAS No. 1699717-32-2

BAY-545( —— )

Catalog No. M21950 CAS No. 1699717-32-2

BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 181 In Stock
5MG 164 In Stock
10MG 247 In Stock
25MG 444 In Stock
50MG 625 In Stock
100MG 870 In Stock
200MG 1172 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BAY-545
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).
  • Description
    BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).
  • In Vitro
    BAY-545 is selective at A2B adenosine receptor over A1, A2A, and A3 adenosine receptor, with IC50s of 1300 nM (Human A1 adenosine receptor), 820 nM (Human A2A adenosine receptor), 470 nM (Mouse A2A adenosine receptor) and 750 nM (Rat A2A adenosine receptor).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Adenosine Receptor
  • Recptor
    A2B?adenosine receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1699717-32-2
  • Formula Weight
    433.45
  • Molecular Formula
    C18H22F3N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:145 mg/ml(334.53 mM)
  • SMILES
    CCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.H?rter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem. 2019 Feb 1;163:763-778.
molnova catalog
related products
  • KI-7

    KI-7 is an adenosine A2B receptor positive allosteric modulator.

  • GR-79236

    A potent and selective Adenosine A1 receptor agonist with Ki of 3.1 nM.

  • A2A receptor antagon...

    A2A receptor antagonist 1 is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.