Vorolanib

CAS No. 1013920-15-4

Vorolanib( CM082,X-82 )

Catalog No. M21932 CAS No. 1013920-15-4

Vorolanib is an orally active VEGFR/PDGFR dual inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 357 In Stock
25MG 597 In Stock
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Biological Information

  • Product Name
    Vorolanib
  • Note
    Research use only, not for human use.
  • Brief Description
    Vorolanib is an orally active VEGFR/PDGFR dual inhibitor.
  • Description
    Vorolanib is an orally active VEGFR/PDGFR dual inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CM082,X-82
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR|PDGFR
  • Research Area
    Urinary system/Cancer
  • Indication
    Renal Cell Cancer Metastatic

Chemical Information

  • CAS Number
    1013920-15-4
  • Formula Weight
    439.48
  • Molecular Formula
    C23H26FN5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:22 mg/ml (50.06 mM; Need ultrasonic)
  • SMILES
    CN(C)C(=O)N1CC[C@@H](C1)NC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bendell JC, et al. Phase I, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Vorolanib in Patients with Advanced Solid Tumors. Oncologist. 2019 Apr;24(4):455-e121.
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