2-O-Acetyl-20-hydroxyecdysone( —— )

Catalog No. M21780 CAS No. 19536-25-5

2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

2-O-Acetyl-20-hydroxyecdysone
Note

Research use only, not for human use.
Brief Description

2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity.
Description

2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42 (Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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Chemical Information

CAS Number

19536-25-5
Formula Weight

522.67
Molecular Formula

C??H??O?
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (191.33 mM)
SMILES

C[C@@]12[C@@](C(C=C3[C@]2([H])CC[C@@]4(C)[C@@]3(O)CC[C@]4([H])[C@](O)(C)[C@H](O)CCC(O)(C)C)=O)([H])C[C@@H](O)[C@@H](OC(C)=O)C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Yang SG, et al. Diverse ecdysterones show different effects on amyloid-β42 aggregation but all uniformly inhibit amyloid-β42-induced cytotoxicity. J Alzheimers Dis. 2010;22(1):107-17.

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