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Ozenoxacin

CAS No. 245765-41-7

Ozenoxacin( T-3912 )

Catalog No. M21673 CAS No. 245765-41-7

Ozenoxacin is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Ozenoxacin
  • Note
    Research use only, not for human use.
  • Brief Description
    Ozenoxacin is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.
  • Description
    Ozenoxacin is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.(In Vitro):Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10 10 and 5.3 × 10 10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin.
  • In Vitro
    Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10?10 and 5.3 × 10?10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin.
  • In Vivo
    ——
  • Synonyms
    T-3912
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    Infection
  • Indication
    Impetigo

Chemical Information

  • CAS Number
    245765-41-7
  • Formula Weight
    363.41
  • Molecular Formula
    C21H21N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 5 mg/mL (13.76 mM; Need ultrasonic and warming)
  • SMILES
    O=C(C1=CN(C2CC2)C3=C(C=CC(C4=CC(C)=C(NC)N=C4)=C3C)C1=O)O
  • Chemical Name
    1-cyclopropyl-8-methyl-7-(5-methyl-6-(methylamino)pyridin-3-yl)-4-oxo-14-dihydroquinoline-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.López Y et al. In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria. Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92.
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