TPCK

CAS No. 402-71-1

TPCK( —— )

Catalog No. M21646 CAS No. 402-71-1

TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation apoptosis and tumorigenesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 37 In Stock
50MG 51 In Stock
100MG 74 In Stock
200MG 107 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TPCK
  • Note
    Research use only, not for human use.
  • Brief Description
    TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation apoptosis and tumorigenesis.
  • Description
    TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation apoptosis and tumorigenesis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    chymotrypsin-like proteases
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    402-71-1
  • Formula Weight
    351.84
  • Molecular Formula
    C17H18ClNO3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (284.21 mM)
  • SMILES
    Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)CCl
  • Chemical Name
    (S)-N-(4-chloro-3-oxo-1-phenylbutan-2-yl)-4-methylbenzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rana Anjum Eunice Paeet al.TPCK Inhibits AGC Kinases by Direct Activation Loop Adduction at Phenylalanine-Directed Cysteine Residues. FEBS Lett. 2012 Sep 21;586(19):3471-6.
molnova catalog
related products
  • WAY-659694

    WAY-659694 shows moderate acute anti-inflammatory activity and analgesic activity in vivo.

  • Epoxomicin

    Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome.

  • Anemarsaponin C

    Timosaponin C is isolated from Rhizoma Anemarrhenae. Timosaponin C shows weaker NO inhibition in N9 microglial cells.