BNC210( H-Ile-Trp-OH | IW-2143 )

Catalog No. M21627 CAS No. 13589-06-5

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	43	In Stock
25MG	79	In Stock
50MG	127	In Stock
100MG	217	In Stock
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Biological Information

Product Name

BNC210
Note

Research use only, not for human use.
Brief Description

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
Description

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
In Vitro

——
In Vivo

——
Synonyms

H-Ile-Trp-OH | IW-2143
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

α7 nAChR
Research Area

Neurological Disease
Indication

Post-Traumatic Stress Disorder

Chemical Information

CAS Number

13589-06-5
Formula Weight

317.38
Molecular Formula

C17H23N3O3
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (393.85 mM; Need ultrasonic)
SMILES

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Toby Wise Fiona Patrick Nicholas Meyeret al.Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder.Biol Psychiatry. 2020 May 15;87(10):908-915.

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