46-Dioxoheptanoic acid

CAS No. 51568-18-4

46-Dioxoheptanoic acid( Succinylacetone )

Catalog No. M21430 CAS No. 51568-18-4

46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
10MG 38 In Stock
25MG 59 In Stock
50MG 83 In Stock
100MG 137 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    46-Dioxoheptanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
  • Description
    46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
  • In Vitro
    4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture.
  • In Vivo
    ——
  • Synonyms
    Succinylacetone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    51568-18-4
  • Formula Weight
    158.15
  • Molecular Formula
    C7H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:1 mg/mL (632.31 mM)
  • SMILES
    CC(CC(CCC(O)=O)=O)=O
  • Chemical Name
    46-dioxoheptanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ebert PS et al. Succinylacetone a potent inhibitor of heme biosynthesis: effect on cell growth heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90.
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