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573'4'-Tetramethoxyflavone

CAS No. 855-97-0

573'4'-Tetramethoxyflavone( —— )

Catalog No. M21428 CAS No. 855-97-0

573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    573'4'-Tetramethoxyflavone
  • Note
    Research use only, not for human use.
  • Brief Description
    573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.
  • Description
    573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.
  • In Vitro
    Cell Line:Concentration:Incubation Time:Result:Western Blot Analysis Cell Line:Chondrocytes Concentration:5-20 μg/mL Incubation Time:4 h Result:Increased the protein level of Bcl-2 and XBP1s.Decreased the expression of pro-apoptotic factors CHOP/caspase-3 and stress kinase JNK.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal|Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    855-97-0
  • Formula Weight
    342.35
  • Molecular Formula
    C19H18O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:8.33 mg/mL (24.33 mM)
  • SMILES
    COc(cc1OC)cc(OC(c(cc2)cc(OC)c2OC)=C2)c1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu L et al. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro. Biochem Biophys Res Commun. 2014 Sep 26;452(3):682-8.
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