573'4'-Tetramethoxyflavone

CAS No. 855-97-0

573'4'-Tetramethoxyflavone( —— )

Catalog No. M21428 CAS No. 855-97-0

573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 42 In Stock
25MG 69 In Stock
50MG 110 In Stock
100MG 161 In Stock
200MG 241 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    573'4'-Tetramethoxyflavone
  • Note
    Research use only, not for human use.
  • Brief Description
    573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.
  • Description
    573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.
  • In Vitro
    Cell Line:Concentration:Incubation Time:Result:Western Blot Analysis Cell Line:Chondrocytes Concentration:5-20 μg/mL Incubation Time:4 h Result:Increased the protein level of Bcl-2 and XBP1s.Decreased the expression of pro-apoptotic factors CHOP/caspase-3 and stress kinase JNK.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal|Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    855-97-0
  • Formula Weight
    342.35
  • Molecular Formula
    C19H18O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:8.33 mg/mL (24.33 mM)
  • SMILES
    COc(cc1OC)cc(OC(c(cc2)cc(OC)c2OC)=C2)c1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu L et al. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro. Biochem Biophys Res Commun. 2014 Sep 26;452(3):682-8.
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