H-HoArg-OH

CAS No. 156-86-5

H-HoArg-OH( —— )

Catalog No. M21407 CAS No. 156-86-5

H-HoArg-OH a homologue arginine is a strong inhibitor of human bone and liver alkaline phosphatase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    H-HoArg-OH
  • Note
    Research use only, not for human use.
  • Brief Description
    H-HoArg-OH a homologue arginine is a strong inhibitor of human bone and liver alkaline phosphatase.
  • Description
    H-HoArg-OH a homologue arginine is a strong inhibitor of human bone and liver alkaline phosphatase.
  • In Vitro
    It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    alkaline phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    156-86-5
  • Formula Weight
    188.23
  • Molecular Formula
    C7H16N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:37 mg/mL (196.56 mM)
  • SMILES
    N[C@@H](CCCCNC=NN)C(O)=O
  • Chemical Name
    N6-carbamimidoyl-L-lysine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fishman W et al. L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase. Clin Chim Acta. 1970 Aug;29(2):339-41.
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