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BTZO-1
CAS No. 99420-15-2
BTZO-1( —— )
Catalog No. M21169 CAS No. 99420-15-2
BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 78 | In Stock |
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| 25MG | 157 | In Stock |
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| 50MG | 230 | In Stock |
|
| 100MG | 342 | In Stock |
|
| 200MG | 486 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBTZO-1
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NoteResearch use only, not for human use.
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Brief DescriptionBTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
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DescriptionBTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
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In VitroBTZO-1 (0-330 nM; 24 hours) dose-dependently suppressed serum deprivation-induced cardiomyocyte death; the minimum effective concentration (MEC1.5),the concentration of a sample necessary to give a 50% increase in cell viability, is 16 nM.BTZO-1 (0.37 μM; 21 hours) upregulates mRNA protein levels of GST Ya and HO-1 in cardiomyocytes.Cell Viability Assay Cell Line:Primary Neonatal Rat Cardiomyocytes Concentration:0-330 nM Incubation Time:24 hours Result:Suppressed serum deprivation or DOX-induced cell death.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number99420-15-2
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Formula Weight240.29
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Molecular FormulaC13H8N2OS
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Purity>98% (HPLC)
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SolubilityDMSO:8.33 mg/mL (34.67 mM; Need ultrasonic)
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SMILESO=c1nc(-c2ccccn2)sc2ccccc12
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Chemical Name2-Pyridin-2-yl-13-benzothiazin-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kimura H Sato Y Tajima Y et al. BTZO-1 a Cardioprotective Agent Reveals that Macrophage Migration Inhibitory Factor Regulates ARE-Mediated Gene Expression[J]. Chemistry & Biology 2010 17(12):1282-1294.
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