DO1

CAS No. 2581-69-3

DO1( Disperse Orange 1 )

Catalog No. M21106 CAS No. 2581-69-3

DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 29 In Stock
25MG 41 In Stock
50MG 77 In Stock
100MG 116 In Stock
200MG Get Quote In Stock
500MG 290 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    DO1
  • Note
    Research use only, not for human use.
  • Brief Description
    DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.
  • Description
    DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Disperse Orange 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2581-69-3
  • Formula Weight
    318.33
  • Molecular Formula
    C18H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=[N+]([O-])c1ccc(N=Nc2ccc(Nc3ccccc3)cc2)cc1
  • Chemical Name
    4-((4-Nitrophenyl)diazenyl)-N-phenylaniline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Boeddrich A Babila JT Wiglenda Tet al.The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice[J].Cell Chem Biol. 2019 Jan 17 ;26(1):109-120.e7.?
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