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DL-Buthionine-(SR)-sulfoximine

CAS No. 5072-26-4

DL-Buthionine-(SR)-sulfoximine( Butionine sulfoximine | NSC 381100 )

Catalog No. M20963 CAS No. 5072-26-4

DL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DL-Buthionine-(SR)-sulfoximine
  • Note
    Research use only, not for human use.
  • Brief Description
    DL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
  • Description
    DL-Buthionine-(SR)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Butionine sulfoximine | NSC 381100
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    γ-glutamylcysteine synthetase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5072-26-4
  • Formula Weight
    222.31
  • Molecular Formula
    C8H18N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:41.67 mg/mL (187.44 mM; Need ultrasonic)
  • SMILES
    CCCCS(=N)(=O)CCC(N)C(=O)O
  • Chemical Name
    2-amino-4-(butylsulfonimidoyl)butanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Arrick B. A . Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis[J]. Journal of Experimental Medicine 1981 153(3):720-725.
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