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Pyroxamide
CAS No. 382180-17-8
Pyroxamide( —— )
Catalog No. M20956 CAS No. 382180-17-8
Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 71 | In Stock |
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| 25MG | 154 | In Stock |
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| 50MG | 259 | In Stock |
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| 100MG | 458 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePyroxamide
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NoteResearch use only, not for human use.
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Brief DescriptionPyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
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DescriptionPyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
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In VitroCell Viability Assay Cell Line:RD cells; RH30B cells Concentration:1.25-20.0 μM Incubation Time:24 hours; 48 hours; 72 hours Result:Resulted in a cell growth decrease in RD and RH30B cells.Cell Cycle Analysis Cell Line:RD cells; RH30B cells Concentration:10.0 μM; 20.0 μM Incubation Time:48 hours Result:Increased the sub-G1?fractions at 48 hours compared with control samples.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number382180-17-8
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Formula Weight265.31
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Molecular FormulaC13H19N3O3
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (471.15 mM)
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SMILESO=C(CCCCCCC(=O)Nc1cccnc1)NO
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Chemical NameN1-hydroxy-N8-(pyridin-3-yl)octanediamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Butler L M Webb Y Agus D B et al. Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide an inhibitor of histone deacetylase[J]. Clinical Cancer Research 2001 7(4):962-970.
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