Cart
sales@molnova.com
Home - Products - GPCR/G Protein - S1P Receptor - GSK2018682

GSK2018682

CAS No. 1034688-30-6

GSK2018682( —— )

Catalog No. M20904 CAS No. 1034688-30-6

GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 49 In Stock
2MG 29 In Stock
5MG 45 In Stock
10MG 76 In Stock
25MG 148 In Stock
50MG 269 In Stock
100MG 398 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    GSK2018682
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2respectively).
  • Description
    GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2respectively).(In Vitro):GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4.
  • In Vitro
    GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    S1P Receptor
  • Recptor
    S1P
  • Research Area
    Others
  • Indication
    Multiple sclerosis

Chemical Information

  • CAS Number
    1034688-30-6
  • Formula Weight
    440.88
  • Molecular Formula
    C22H21ClN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (283.52 mM)
  • SMILES
    CC(C)Oc1ncc(-c2nc(-c3cccc4c3ccn4CCCC(=O)O)no2)cc1Cl
  • Chemical Name
    4-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-124-oxadiazol-3-yl)-1H-indol-1-yl)butanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu J Gray F Henderson A et al. Safety pharmacokinetics pharmacodynamics and bioavailability of GSK2018682 a sphingosine-1-phosphate receptor modulator in healthy volunteers[J]. Clinical Pharmacology in Drug Development 2014 3(3):170-178.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Ex26

    Ex26 (S1P1-IN-Ex26) is a selective and potent sphingosine 1-phosphate receptor 1 (S1P1) antagonist that disrupts SR-B1-S1PR1 interactions and inhibits S1P-S1PR1 signaling.

  • Maribavir

    Maribavir is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV).

  • CS 2100

    CS 2100 is an S1P1 agonist.

Sign In Join Free