NNC-0640

CAS No. 307986-98-7

NNC-0640( —— )

Catalog No. M20735 CAS No. 307986-98-7

NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 92 In Stock
2MG 56 In Stock
5MG 92 In Stock
10MG 163 In Stock
25MG 297 In Stock
50MG 445 In Stock
100MG 641 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NNC-0640
  • Note
    Research use only, not for human use.
  • Brief Description
    NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
  • Description
    NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Glucagon Receptor
  • Recptor
    human glucagon receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    307986-98-7
  • Formula Weight
    573.67
  • Molecular Formula
    C29H31N7O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (435.79 mM)
  • SMILES
    CS(=O)(=O)c1cccc(NC(=O)N(Cc2ccc(cc2)C(=O)Nc2nn[nH]n2)c2ccc(cc2)C2CCCCC2)c1
  • Chemical Name
    4-[1-(4-Cyclohexylphenyl)-3-(3-methanesulfonylphenyl)ureidomethyl]-N-(2H-tetrazol-5-yl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Song G Yang D Wang Y et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators[J]. Nature 2017.
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