Paquinimod

CAS No. 248282-01-1

Paquinimod( ABR 25757 )

Catalog No. M20732 CAS No. 248282-01-1

Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 80 In Stock
5MG 72 In Stock
10MG 117 In Stock
25MG 218 In Stock
50MG 347 In Stock
100MG 440 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Paquinimod
  • Note
    Research use only, not for human use.
  • Brief Description
    Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
  • Description
    Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ABR 25757
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    S100A9
  • Research Area
    Others
  • Indication
    Systemic scleroderma

Chemical Information

  • CAS Number
    248282-01-1
  • Formula Weight
    350.41
  • Molecular Formula
    C21H22N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (356.72 mM)
  • SMILES
    CCN(C(=O)c1c(O)c2c(CC)cccc2n(C)c1=O)c1ccccc1
  • Chemical Name
    N5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-12-dihydroquinoline-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schelbergen R F Geven E J Van d B M H J et al. Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis[J]. Annals of the Rheumatic Diseases 2015:annrheumdis-2014-206517.
molnova catalog
related products
  • Prosapogenin A

    Prosapogenin A, a natural product from?Veratrum, induces?apoptosis?in human?cancer?cells in vitro via inhibition of the?STAT3?signaling pathway and glycolysis.

  • Lenacapavir

    Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.

  • YM17E

    YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.