Dihexa

CAS No. 1401708-83-5

Dihexa( PNB-0408 | N-hexanoic-Try-Ile-(6)-amino hexanoic amide | Hexanoyl-Tyr-Ile-Ahx-NH2 )

Catalog No. M20716 CAS No. 1401708-83-5

Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 155 In Stock
2MG 83 In Stock
5MG 128 In Stock
10MG 218 In Stock
25MG 376 In Stock
50MG 529 In Stock
100MG 732 In Stock
200MG 1004 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dihexa
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.
  • Description
    Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PNB-0408 | N-hexanoic-Try-Ile-(6)-amino hexanoic amide | Hexanoyl-Tyr-Ile-Ahx-NH2
  • Pathway
    Angiogenesis
  • Target
    c-Met/HGFR
  • Recptor
    HGF
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1401708-83-5
  • Formula Weight
    504.66
  • Molecular Formula
    C27H44N4O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (59.45 mM)
  • SMILES
    CCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCCCC(N)=O
  • Chemical Name
    6-[(2S3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mccoy A T Benoist C C Wright J W et al. Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents[J]. Journal of Pharmacology and Experimental Therapeutics 2013 344(1):141-154.
molnova catalog
related products
  • AMG-208

    AMG-208 is a potent, small-molecule c-Met inhibitor with IC50 of 5.2 nM against wt MET kinase, also inhibits VEGFR2 with IC50 of 112 nM.

  • Grazoprevir

    MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.

  • PF-04217903 methanes...

    PF-04217903 is a potent, selective, ATP-competitive c-Met kinase inhibitor with Ki of 4.8 nM.