Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Sodium Channel - Benzamil (hydrochloride)

Benzamil (hydrochloride)

CAS No. 2898-76-2

Benzamil (hydrochloride)( —— )

Catalog No. M20570 CAS No. 2898-76-2

Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 69 In Stock
5MG 48 In Stock
10MG 57 In Stock
25MG 120 In Stock
50MG 222 In Stock
100MG 402 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Benzamil (hydrochloride)
  • Note
    Research use only, not for human use.
  • Brief Description
    Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
  • Description
    Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
  • In Vitro
    Benzamil (Benzylamiloride) inhibits neuronal and heterologously expressed small conductance Ca2+-activated K2+ channels.
  • In Vivo
    Benzamil (Benzylamiloride) (0.7 mg/kg/day; s.c.) treated stroke-prone spontaneously hypertensive rats (SHRSP) survived, on average, until 16.1 weeks of age in SHRSP rats.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    ENaC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2898-76-2
  • Formula Weight
    356.21
  • Molecular Formula
    C13H15Cl2N7O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Nc1nc(N)c(nc1Cl)C(=O)NC(=N)NCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jeong S Lee S H Kim Y O et al. Antinociceptive Effects of Amiloride and Benzamil in Neuropathic Pain Model Rats[J]. Journal of Korean Medical Science 2013 28(8).
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Ademine

    Triamterene is a Potassium-sparing Diuretic.

  • Tetracaine hydrochlo...

    Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

  • VX-150

    VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).

Sign In Join Free