Menadione sodium bisulfite

CAS No. 130-37-0

Menadione sodium bisulfite ( Sodium menadione bisulfite | Vitamin K3 sodium bisulfite )

Catalog No. M20530 CAS No. 130-37-0

Menadione sodium bisulfite(MSB also known as vitamin K3)is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G 32 In Stock

Biological Information

  • Product Name
    Menadione sodium bisulfite
  • Note
    Research use only, not for human use.
  • Brief Description
    Menadione sodium bisulfite(MSB also known as vitamin K3)is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.
  • Description
    Menadione sodium bisulfite(MSB also known as vitamin K3)is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.(In Vitro):Menadione sodium bisulfite (500 μM) treatment and the concomitant ROS increase have an important impact on the photosynthetic activity of the cells. Global and specific antioxidant defences decrease with Menadione sodium bisulfite (500 μM) treatment. Menadione sodium bisulfite and PABA activate similar defense responses (PR, ROS, and HR). Menadione sodium bisulfite enhances resistance, both locally and systemically, to phoma stem canker disease caused by Leptosphaeria maculans. Menadione sodium bisulfite treatment induces resistance against downy mildew in pearl millet. Menadione sodium bisulfite acts through priming of specific sets of the plant innate-defense repertoire. Menadione sodium bisulfite treatment up-regulates the expression of a gene encoding a GRX480 protein, a member of the glutaredoxin family that regulates protein redox state.
  • In Vitro
    Menadione sodium bisulfite (500 μM) treatment and the concomitant ROS increase have an important impact on the photosynthetic activity of the cells. Global and specific antioxidant defences decrease with Menadione sodium bisulfite (500 μM) treatment. Menadione sodium bisulfite and PABA activate similar defense responses (PR, ROS, and HR). Menadione sodium bisulfite enhances resistance, both locally and systemically, to phoma stem canker disease caused by Leptosphaeria maculans. Menadione sodium bisulfite treatment induces resistance against downy mildew in pearl millet. Menadione sodium bisulfite acts through priming of specific sets of the plant innate-defense repertoire. Menadione sodium bisulfite treatment up-regulates the expression of a gene encoding a GRX480 protein, a member of the glutaredoxin family that regulates protein redox state.
  • In Vivo
    ——
  • Synonyms
    Sodium menadione bisulfite | Vitamin K3 sodium bisulfite
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    Vitamin K deficiencyhypothromboplasmiaNatural neonatal bleeding

Chemical Information

  • CAS Number
    130-37-0
  • Formula Weight
    276.24
  • Molecular Formula
    C11H9NaO5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:36 mg/mL (130.32 mM)
  • SMILES
    [Na+].CC1(CC(=O)c2ccccc2C1=O)S([O-])(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yu Z Yudan Z Zhuoyi W et al. Menadione sodium bisulfite inhibits the toxic aggregation of amyloid-β(1–42)[J]. Biochimica et Biophysica Acta (BBA) - General Subjects 2018 1862(10):2226-2235.
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