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Home - Products - PI3K/Akt/mTOR signaling - GSK-3 - VP3.15 dihydrobromide

VP3.15 dihydrobromide

CAS No. 1281681-33-1

VP3.15 dihydrobromide( —— )

Catalog No. M20527 CAS No. 1281681-33-1

VP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    VP3.15 dihydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    VP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)
  • Description
    VP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    GSK-3|PDE7
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1281681-33-1
  • Formula Weight
    528.3
  • Molecular Formula
    C20H24Br2N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (118.30 mM)
  • SMILES
    Br.Br.C(CN1CCOCC1)N=c1nc(-c2ccccc2)n(s1)-c1ccccc1
  • Chemical Name
    (23-Diphenyl-2H-[124]thiadiazol-5-ylidene)-(2-morpholin-4-yl-ethyl)-amine Dihydrobromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Medina-Rodríguez Eva María Bribián Ana Boyd A et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis[J]. Scientific Reports 2017 7:43545.
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