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VP3.15 dihydrobromide
CAS No. 1281681-33-1
VP3.15 dihydrobromide( —— )
Catalog No. M20527 CAS No. 1281681-33-1
VP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 36 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 130 | In Stock |
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| 50MG | 221 | In Stock |
|
| 100MG | 328 | In Stock |
|
| 200MG | 458 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVP3.15 dihydrobromide
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NoteResearch use only, not for human use.
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Brief DescriptionVP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)
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DescriptionVP3.15 dihydrobromide is a potent orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM 0.88 μMrespectively.)
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3|PDE7
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Research Area——
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Indication——
Chemical Information
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CAS Number1281681-33-1
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Formula Weight528.3
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Molecular FormulaC20H24Br2N4OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (118.30 mM)
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SMILESBr.Br.C(CN1CCOCC1)N=c1nc(-c2ccccc2)n(s1)-c1ccccc1
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Chemical Name(23-Diphenyl-2H-[124]thiadiazol-5-ylidene)-(2-morpholin-4-yl-ethyl)-amine Dihydrobromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Medina-Rodríguez Eva María Bribián Ana Boyd A et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis[J]. Scientific Reports 2017 7:43545.
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