9-Methoxycamptothecin?
CAS No. 39026-92-1
9-Methoxycamptothecin?( —— )
Catalog No. M20440 CAS No. 39026-92-1
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 46 | In Stock |
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| 50MG | 67 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name9-Methoxycamptothecin?
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NoteResearch use only, not for human use.
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Brief Description9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
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Description9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number39026-92-1
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Formula Weight378.38
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Molecular FormulaC21H18N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (264.28 mM)
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SMILESCC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc(OC)c4cc3Cn1c2=O
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Chemical Name(S)-4-ethyl-4-hydroxy-10-methoxy-112-dihydro-14H-pyrano[3'4':67]indolizino[12-b]quinoline-314(4H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Gimatecan
Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.
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Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
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Idarubicin
Idarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
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