2-Furoic acid( Furan-2-carboxylic acid )

Catalog No. M20299 CAS No. 88-14-2

2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

2-Furoic acid
Note

Research use only, not for human use.
Brief Description

2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.
Description

2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.
In Vitro

——
In Vivo

2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities.2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice.
Synonyms

Furan-2-carboxylic acid
Pathway

Microbiology/Virology
Target

Antifection
Recptor

Antifection
Research Area

——
Indication

——

Chemical Information

CAS Number

88-14-2
Formula Weight

112.08
Molecular Formula

C5H4O3?
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL?(892.22 mM)
SMILES

OC(=O)c1ccco1
Chemical Name

2-Furancarboxylic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hara S Isoda R Tahvanainen T et al. Trace Amounts of Furan-2-Carboxylic Acids Determine the Quality of Solid Agar Plates for Bacterial Culture[J]. Plos One 2012 7(7):e41142.

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