Methyl cinnamate

CAS No. 103-26-4

Methyl cinnamate( —— )

Catalog No. M20228 CAS No. 103-26-4

Methyl cinnamate a tyrosinase inhibitor and a flavoring compound has antimicrobial antiadipogenic vasorelaxant and anti-inflammatory effects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Methyl cinnamate
  • Note
    Research use only, not for human use.
  • Brief Description
    Methyl cinnamate a tyrosinase inhibitor and a flavoring compound has antimicrobial antiadipogenic vasorelaxant and anti-inflammatory effects.
  • Description
    Methyl cinnamate a tyrosinase inhibitor and a flavoring compound has antimicrobial antiadipogenic vasorelaxant and anti-inflammatory effects.(In Vitro):In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2 AMPK signaling cascade involved in the regulation of adipogenesis.
  • In Vitro
    In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2?AMPK signaling cascade involved in the regulation of adipogenesis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Tyrosinase
  • Recptor
    Tyrosinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    103-26-4
  • Formula Weight
    162.19
  • Molecular Formula
    C10H10O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 30 mg/mL (184.97 mM);Water: Insoluble
  • SMILES
    COC(=O)\C=C\c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vasconcelos-Silva AA et al. Vasorelaxation induced by methyl cinnamate the major constituent of the essential oil of Ocimum micranthum in rat isolated aorta. Clin Exp Pharmacol Physiol. 2014 Oct;41(10):755-62.
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