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PKC-theta inhibitor

CAS No. 736048-65-0

PKC-theta inhibitor( —— )

Catalog No. M20187 CAS No. 736048-65-0

PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 274 In Stock
5MG 250 In Stock
10MG 330 In Stock
25MG 467 In Stock
50MG 600 In Stock
100MG 923 In Stock
200MG 1237 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    PKC-theta inhibitor
  • Note
    Research use only, not for human use.
  • Brief Description
    PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.
  • Description
    PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKCθ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    736048-65-0
  • Formula Weight
    454.4
  • Molecular Formula
    C20H25F3N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(137.53 mM)
  • SMILES
    NCC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+]([O-])=O)CC1
  • Chemical Name
    N4-((4-(aminomethyl)cyclohexyl)methyl)-5-nitro-N2-(2-(trifluoromethoxy)benzyl)pyrimidine-24-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cywin CL et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30.
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