PKC-theta inhibitor

CAS No. 736048-65-0

PKC-theta inhibitor( —— )

Catalog No. M20187 CAS No. 736048-65-0

PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PKC-theta inhibitor
  • Note
    Research use only, not for human use.
  • Brief Description
    PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.
  • Description
    PKC-theta inhibitor is PKC-θinhibitor with an IC50 of 12 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKCθ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    736048-65-0
  • Formula Weight
    454.4
  • Molecular Formula
    C20H25F3N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(137.53 mM)
  • SMILES
    NCC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+]([O-])=O)CC1
  • Chemical Name
    N4-((4-(aminomethyl)cyclohexyl)methyl)-5-nitro-N2-(2-(trifluoromethoxy)benzyl)pyrimidine-24-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cywin CL et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30.
molnova catalog
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