ML367( —— )

Catalog No. M20178 CAS No. 381168-77-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

ML367
Note

Research use only, not for human use.
Brief Description

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
Description

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
In Vitro

Western Blot Analysis Cell Line:HEK293T cells Concentration:0-40 μM in the presence or absence of 20 μM 5-Furd Incubation Time:16 hours Result:Inhibited the increased ATAD5 protein levels induced by 5-Furd.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

ATAD5
Research Area

——
Indication

——

CAS Number

381168-77-0
Formula Weight

334.32
Molecular Formula

C19H12F2N4
Purity

>98% (HPLC)
Solubility

DMSO:120 mg/mL?(358.94 mM)
SMILES

Fc1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1F
Chemical Name

(S)-9b-(4-Chlorophenyl)-1-(34-difluorobenzoyl)-23-dihydro-1H-imidazo[21-a]isoindol-5(9bH)-one

1.Rohde JM et al. Discovery of ML367 inhibitor of ATAD5 stabilization. Probe Reports from the NIH Molecular Libraries Program.

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