Cart
sales@molnova.com
AMAROGENTIN
CAS No. 21018-84-8
AMAROGENTIN( —— )
Catalog No. M20171 CAS No. 21018-84-8
Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 77 | In Stock |
|
| 25MG | 155 | In Stock |
|
| 50MG | 212 | In Stock |
|
| 100MG | 299 | In Stock |
|
| 200MG | 454 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAMAROGENTIN
-
NoteResearch use only, not for human use.
-
Brief DescriptionAmarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis
-
DescriptionAmarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis.
-
In Vitro——
-
In VivoAnimal Model:Carbon tetrachloride (HY-Y0298)-induced liver fibrosis mice modelDosage:100 mg/kg Administration:p.o.Result:Decreased hepatic α-SMA and TGF-β1 expression.Inhibited phosphorylation of JNK, ERK, and p38.
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetAMPK
-
RecptorAMPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number21018-84-8
-
Formula Weight586.54
-
Molecular FormulaC29H30O13
-
Purity>98% (HPLC)
-
SolubilityDMSO:2 mg/mL?(3.4 mM)
-
SMILES[H][C@@]12CCOC(=O)C1=CO[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC(=O)c1c(O)cc(O)cc1-c1cccc(O)c1)[C@@H]2C=C
-
Chemical Name(11'-Biphenyl)-2-carboxylic acid 33'5-trihydroxy- 2-ester with 5-ethenyl-6-(beta-D-glucopyranosyloxy)-44a56-tetrahydro-1H3H-pyrano(34-c)pyran-1-one (4aS-(4aalpha5beta6alpha))-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Shantanu S Khushboo B Durai S et al. The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin a Secoiridoid Glycoside from Swertia chirayita[J]. PLoS ONE 2014 9(3):e90637-.
molnova catalog
related products
-
Karanjin
Karanjin is a flavonoid?obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity.
-
BC1618
BC1618 is an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling.
-
Buformin hydrochlori...
Buformin hydrochloride is a potent AMPK activator,an oral antidiabetic drug of the biguanide class.
